Physical Education
Mohammad Hoseinzadeh; Amir Rashidlamir; farida sadeghi fazel; Rambod Khajei
Volume 27, Issue 3 , September and October 2020, , Pages 340-346
Abstract
Background and purpose:Irisin, which is released in response to physical activity, has recently been reported as the therapeutic target in metabolic disorders. The present study attempts to discover the effect of eight weeks’ resistance or endurance training on the irisin level in rats’ gastrocnemius ...
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Background and purpose:Irisin, which is released in response to physical activity, has recently been reported as the therapeutic target in metabolic disorders. The present study attempts to discover the effect of eight weeks’ resistance or endurance training on the irisin level in rats’ gastrocnemius and liver.Materials and methods:To this purpose,15 male rats were randomly assigned to three groups of 5: the resistance group, the endurance group, and the control group. For 8 weeks, the resistance group did the activities on the treadmill and the endurance group on a one-meter-long ladder with 85 steep, while the control group did not receive any training. 72 hours after their last training session, the subjects were anaesthetized and their liver and gastrocnemius were removed. A Shapiro-Wilk test was run to determine the normal distribution of data, and a one-way ANOVA and a Tukey test were applied to analyze the data(P ≥ 0.05).Results: The normal distribution having been approved via the Shapiro-Wilk test, the one-way ANOVA showed a significant difference in the irisin levels between the groups’ livers and gastrocnemii (P =0.001 and P -0.016, respectively). The Tukey test revealed a significant rise in the liver tissue of the resistance group and endurance group in comparison to the control group (P =0.001 and P =0.742, respectively).Conclusion:According to this study, both resistance and endurance training can help significantly increase the irisin level of both the liver and the gastrocnemius, indicating how physical activity can help in the prevention and treatment of metabolic illnesses.
Physical Education
Mohammad Hoseinzadeh; Amir Rashidlamir; Seyed Mahmud Hejazi
Volume 25, Issue 5 , November and December 2018, , Pages 629-637
Abstract
Background and purpose: Fibronectin transmembrane type III domain-containing protein 5 (FNDC5) is a characteristic factor in distinguishing skeletal muscle cells. Since the productive effects of regular exercise are conveyed through the skeletal muscle, this study aims to compare the effects of progressive ...
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Background and purpose: Fibronectin transmembrane type III domain-containing protein 5 (FNDC5) is a characteristic factor in distinguishing skeletal muscle cells. Since the productive effects of regular exercise are conveyed through the skeletal muscle, this study aims to compare the effects of progressive endurance and resistance training on FNDC5 gene expression in male rats’ gastrocnemius muscles.Materials and Methods: 15 male rats were randomly assigned to three equal groups of: control, endurance training and resistance training. The endurance group performed 8 weeks of training on the treadmill. The resistance group did their exercises for eight weeks on a three-session-per-week basis on a one-meter-high ladder with 85○ slope. All subjects were anesthetized 72 hours after the experiment finished and the gastrocnemius removed. The level of FNDC5 expression was measured through real-time PCR method and one-way ANOVA applied to analyze the data. Level of significance was set to P≥0.05.Results: One-way ANOVA showed a significant difference in FNDC5 expression among the groups (P=0.001, F=31.791). A subsequent Tukey test application showed FNDC5 gene expression of the gastrocnemius muscle was significantly higher in the resistance and endurance training groups than in the control group (P
Physical Education
Leili Zeiaadini Dashtkhaki; Amir Rashidlamir; Said Naghibi
Volume 25, Issue 4 , September and October 2018, , Pages 473-485
Abstract
Cardiac rehabilitation program aimed at reducing secondary risk factors and improving function in patients undergoing coronary artery bypass grafting run which finally may delay or reduce mortality patients. A key component of this program is exercise. The aim of this study was to evaluate the effect ...
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Cardiac rehabilitation program aimed at reducing secondary risk factors and improving function in patients undergoing coronary artery bypass grafting run which finally may delay or reduce mortality patients. A key component of this program is exercise. The aim of this study was to evaluate the effect of aquatic and dryland training on ABCG8 gene expression in middle-aged women’s peripheral blood mononuclear cells after coronary artery bypass grafting. 30 middle-aged women with cardiovascular disease were divided into three groups including control, aquatic and dryland resistance training. The program lasted for eight weeks of resistance training (3 sessions per week/ 60 minutes per session) and started with 60% of 1RM. Fasting blood samples were taken from all participants 48 hours both prior to the beginning of the training program and after the last training session. ABCG8 relative gene expression was detected by Real-time PCR method. Repeated measures and paired t-test with a significance level of p≤ 0.05 were used to determine differences between and within groups. Repeated measures test showed a significant increase in the relative ABCG8 gene expression in both the aquatic and dryland training groups (P= 0.001). Moreover, paired-samples t-test showed a significant difference in aquatic and dryland training groups regarding ABCG8 gene expression (P= 0.001; P= 0.001). It can be concluded that both training programs on land and water training, increase ABCG8 gene expression in middle-aged women after coronary artery bypass and a possible reverse cholesterol transport process can be improved.
Physical Education
Asra Askari; Amir Rashidlamir; Nahid Bijeh; Majid momeni-moghaddam
Volume 25, Issue 3 , July and August 2018, , Pages 451-460
Abstract
Background:Neurotrophin-3 is among the biomarkers studied in MS.Regarding the fact that Exercise training has been proposed as an effective non-drug way of treating Multiple Sclerosis(MS),the present study aims at investigatingthe effect of eight weeks’ aquatic exercise and resistance training ...
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Background:Neurotrophin-3 is among the biomarkers studied in MS.Regarding the fact that Exercise training has been proposed as an effective non-drug way of treating Multiple Sclerosis(MS),the present study aims at investigatingthe effect of eight weeks’ aquatic exercise and resistance training programs on the plasmatic levels and gene expression of neurotrophin-3in MS patients.Materials and methods:To the aims of the present study,30women with MS were randomly selected and assigned to three groups:the control group,resistance training group,and aquatic exercise group. Resistance training and aquatic exercise programs were used for 8weeks.After separating plasma and PBMNcells,plasmatic levels and the expression of neurotrophin-3gene were measured via ELISA and real-timePCR,respectively.Inorder to compare the means,plasmatic levels and the gene expression of neurotrophin-3of the three groups were Analyzed by the ANCOVAtest at the significance level of p≤0.05through SPSS18. Results:The results showed a significant increase in plasma levels neurotrophin-3of the three groups (p=0.001).The Scheffe post hoc test was significant in two by two comparisons of the aquatic group and resistance training group with the control group (p=0.001,p=0.001,respectively).However,the difference between the aquatic and resistance groups was not significant(p=0.329).Moreover,there was a significant increase in the gene expression of neurotrophin-3of the three groups(p=0.001).Based on the Scheffe test,the mean differences between the aquatic and resistance groups,and the control group were(p=0.053,p=0.001,respectively).However,non-significant differences in the gene expression of neurotrophin-3were shown between the aquatic group and the resistance group(p=0.08).Conclusion:The findings of the present study indicated that both the resistance training and the aquatic exercise can increase plasmatic levels and the gene expression of neurotrophin-3in MS patients.
Amir Rashid Lamir; Mohsen Dehbashi; Bahareh Ketabdar
Volume 23, Issue 1 , May and June 2016, , Pages 6-13
Abstract
Background & Objectives: For the past 50 years, anabolic steroids have been at the forefront of the controversy due to their various effects on athletes' performance. So the aim of the present study was to examine the effects of anabolic steroids abuse, during and after the withdrawal of the drug ...
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Background & Objectives: For the past 50 years, anabolic steroids have been at the forefront of the controversy due to their various effects on athletes' performance. So the aim of the present study was to examine the effects of anabolic steroids abuse, during and after the withdrawal of the drug usage, on liver enzymes and blood albumin of bodybuilders. Materials & Methods: The study is causative-comparative research, and 40 males (Age: 26.62±6.8 years, height: 175.89±9.2 cm, weight: 77.17±12.7) were participated in this study, who were divided into four groups of ten members: athletes are using steroids, athletes with a history of drug usage who had given away its usage at least for 2 months, athletes with a history of at least 6 months of giving away using steroid and athletes with no history of steroid use. 12-hour fasting blood samples were collected at eight o'clock in the morning, and the data were analyzed using one-way ANOVA and a post hoc test. Results: The results of this study showed higher degradation of both enzymes (ALT, AST) in the first group as compared to the other groups (p<%5). The destruction of these two enzymes (AST, ALT) was higher in second group as compared to the third and fourth groups (p<%5). However, the destruction of the two enzymes (ALT, AST) in the third group was not significant as compared to the fourth group. (p<%5). Albumin and (ALP) levels were normal in all groups and their changes were not significant (p>%5). Conclusion: Steroid drugs have devastating effects on the liver cells. So those, even after two months of stopping drug consumption, their side effects are still apparent in athletes who had used them. But it seems that their negative effects on liver enzymes decrease over time.